Colistin FDA Link

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

Also Known As:

Coly-Mycin; Colimycin; Colisticin; Colistin Sulfate; Totazina; Sulfate, Colistin; Polymyxin E

Pharmalogical Action Categories:

Anti-Bacterial Agents

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Polymyxins: 729
      - Colistin: 2679
Lipids: 114793
- Lipopeptides: 626
  - Polymyxins: 729
    - Colistin: 2679
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 414
        Polymyxins: 729
        Colistin: 2679
- Peptides: 82426
  - Antimicrobial Peptides: 3727
    - Antimicrobial Cationic Peptides: 414
      - Polymyxins: 729
        Colistin: 2679
  - Cyclic Peptides: 530
    - Polymyxins: 729
      - Colistin: 2679
  - Antimicrobial Cationic Peptides: 414
    - Polymyxins: 729
      - Colistin: 2679

D O Engin Selected Research

D O Engin Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure